DNA’s crooked path
نویسندگان
چکیده
منابع مشابه
Orientation Tuning—A Crooked Path to the Straight and Narrow
Neurons in visual cortex are selective for the orientation of a visual stimulus, while the receptive fields of their thalamic input are circular. Cortical orientation selectivity arises from the organization of both thalamic input and local cortical circuits. In this issue of Neuron, Schummers and colleagues provide evidence that the local circuit mechanisms contributing to orientation selectiv...
متن کاملCarbamoyl phosphate synthetase: a crooked path from substrates to products.
The formation of carbamoyl phosphate is catalyzed by a single enzyme using glutamine, bicarbonate and two molecules of ATP via a reaction mechanism that requires a minimum of four consecutive reactions and three unstable intermediates. The recently determined X-ray crystal structure of carbamoyl phosphate synthetase has revealed the location of three separate active sites connected by two molec...
متن کاملThe crooked nose
The crooked nose is unquestionably the most severe deformity of the nasal septum due to the simultaneous involvement of very important functional and aesthetic elements. As everyday interpersonal relations are primarily conducted face-to-face, deviation of the nasal pyramid from the median line is immediately obvious even to the least observant. The surgical procedures used to address this path...
متن کاملCrooked Diagrams with Few Slopes
A natural and practical criterion in the preparation of diagrams of ordered sets is to minimize the number of different slopes used for the edges. Any diagram requires at least the maximum number of upper covers (or of lower covers) of any element. While this maximum degree is not always enough we show that it is as long as any edge joining a covering pair may be bent, to produce a crooked diag...
متن کاملTooth development in the 'crooked' mouse.
The semidominant gene 'crooked' (Cd) in the mouse produces anomalies of the axial skeleton (resulting in a crooked tail), microphthalmia and dental abnormalities, including small molars with simplified cusp patterns that are equivalent to patterns passed through during normal morphodifferentiation. A series of embryonic litters from Cd/+ xCd/ + matings was used to investigate the embryological ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Reviews Physics
سال: 2019
ISSN: 2522-5820
DOI: 10.1038/s42254-019-0028-4